Poly-l-lactic acid Dermal Filler

Ingredient: Poly-l-lactic acid 50%, Sodium carboxymethyl cellulose, Mannitol

Specification: 150mg, 180mg,350mg

Package: Bottle

Application Area: Combined to make water and light, tighten and lift the skin, stimulate collagen, fill wrinkles and so on.



Product Details

Product Introduction:

Poly-L-lactic acid is a synthetic, biodegradable polymer widely recognized for its medical safety and compatibility. Historically used in absorbable sutures, PLLA has been adapted into a dermal filler formulation that provides structural support to aging skin.

When injected, PLLA particles trigger the skin’s fibroblasts to produce new collagen fibers, gradually restoring volume, elasticity, and firmness. Over time, the PLLA microspheres are absorbed and metabolized by the body, leaving behind endogenous collagen that maintains long-term results.

This regenerative mechanism differentiates PLLA from traditional fillers: it rebuilds the skin’s framework rather than simply filling spaces, making it ideal for patients seeking subtle, natural, and durable rejuvenation.


Product Display:

Poly-l-lactic acid Dermal Filler


Product Details:

Type

PLLA Filler

Ingredient

Hyaluronic 26mg/ml, hydroxyapatite 30%

Specification

150mg, 180mg,350mg

Effect area

Different uses, different layers
Dermis 5-6mL redissolve,
Subcutaneous: 3-4 ml resolution,
Periosteal ligament: 3mL resolubilization

Application area

Combined to make water and light, tighten and lift the skin, stimulate collagen, fill wrinkles and so on

How to choose

Moderate to severe naso-lip wrinkles

Package

Bottle

Storage

Cool, dry environment

Recommended
Use quantity

1-2 pc/time

Recommended interval

12-24 months

Lasting time

12-24 months

Microsphere size

More uniform particle size; D10 is greater than 10μm
D50:15 to 30 microns
D90 not greater than 50μm; 10-50μm not less than 90%

Characteristic viscosity

1.2-1.4dL/g


Product Package:

Poly-l-lactic acid Dermal Filler


Customer Feedback:

Customer Feedback

Customer Feedback


Key Advantages of PLLA Dermal Fillers

  1. Long-Lasting Results
    Unlike temporary fillers that last 6–12 months, PLLA can provide visible improvement for 18–24 months or longer, thanks to collagen stimulation.

  2. Natural-Looking Enhancement
    The volumization comes from the body’s own collagen, ensuring results appear soft, balanced, and authentic.

  3. Biocompatible and Safe
    PLLA is biodegradable, FDA-approved, and clinically proven for decades in medical applications, minimizing risk of adverse reactions.

  4. Comprehensive Rejuvenation
    In addition to adding volume, PLLA improves skin thickness, elasticity, and texture, enhancing overall facial quality.

  5. Customizable Treatment
    The gradual results allow practitioners to tailor injections and session frequency to each patient’s unique anatomy and aesthetic goals.

  6. Versatile Applications
    PLLA fillers can treat midface volume loss, cheek hollowing, nasolabial folds, jawline contouring, and even non-surgical buttock enhancement, making them highly adaptable.


Development Process:

Development Process


The Future of Aesthetic Rejuvenation:

Poly-L-lactic acid dermal fillers represent a shift from temporary correction to regenerative enhancement. They align with modern beauty ideals, emphasizing natural results, patient comfort, and long-term improvement.

Emerging applications combine PLLA with energy-based devices or complementary fillers, enabling holistic rejuvenation that addresses volume, texture, and skin quality simultaneously.

As regenerative aesthetics continues to evolve, PLLA is positioned at the forefront — bridging science and artistry to create timeless, biologically harmonious beauty.


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