Cross Linked Hyaluronic Acid Dermal Filler

2025/04/15 13:15

Cross linked gel products are divided into single and double according to different processes and gel states, and according to different injection levels at the site of gel use, they are divided into five categories: sub-skin (D24+, S24+), deep(D24, S24), derm (D22, S22), fineD20, HD20) and micro-crosslinked (D12).

In order to fill the lips, our company specially launched HD20 products, adding vitamins on the basis of D20 products, which can effectively avoid inflammation and promote cell regeneration.


Cross Linked Hyaluronic Acid Dermal Filler


Here are the detailed differences between the five categories:


Type

Sub-skin
Deep
DermFine
Lip filler
IngredientCross Linked Hyaluronic Acid Dermal FillerCross Linked Hyaluronic Acid Dermal Filler,B12
Specification1ml, 2ml, 3ml, 5ml, 10ml, 20ml, 50ml1ml
Cross LinkBDDE chemical cross link
TextureGel
Elasticity550 Pa-700 Pa500 Pa-650 Pa250Pa-400 Pa50 Pa-200 Pa50 Pa-200 Pa
Viscosity180 Pa-280 Pa150 Pa-250 Pa40 Pa-100 Pa20 Pa-40 Pa20 Pa-40 Pa
Mean particle size450μm-650μm400μm-600μm200pm-400μm150um-350μm150um-350μm
Effective content24mg/mL24mg/mL22mg/mL20mg/mL20mg/mL
Cross linker residueNo,or≤0.5ug/g
Protein residue≤20μg/g
Endotoxin content<0.5EU/mL
Swelling degree20-3520-4030-5040-6040-60
Extruding force20N-30N20N-30N18N-25N18N-25N15N-22N
Application areaChest, buttocks and other filled and shaped body partsChin, nasal dorsum, nasal column and anterior noseCheek apple muscle, neck lines, forehead lines, eyes, lips, back of hand, nasolabial groove, mouth pouch, puppet lines etcApple cheek muscle, neck lines, forehead lines, eyes, lips, back of hand, nasolabial groove, mouth pouch, marionette lines etcLip
PackageSyringe
StoargeRoom temperature (1-25ºC), cool and dry place
Recommended
Use quantity
1-3 pcs (vary with each individual
Recommended interval12 months




The cross linked sodium hyaluronate gel has an excellent safety profile and is able to meet the therapeutic needs of different areas of the face. Single-phase has excellent tissue integration and a more natural appearance; Biphasic products have excellent lifting power, less pushing force, and more comfortable use. Cross linker residue was not detected (detection limit 0.5μg/g), protein residue 3-5μg/g (detection limit 20μg/g), endomycin content was less than 0.5EU/mL. In addition, the unique micro-crosslinking technology produces a softer texture of the gel, which has a unique effect in the repair of light lines and is not easy to cause picucho. Excellent histocompatibility, more natural repair.


Cross Linked Hyaluronic Acid Dermal Filler


Advantages:

Natural smooth: uniform texture, soft touch after injection, suitable for shallow filling (such as tear furrows, lips, fine lines).

High stability: not easy to spread or shift, maintain a long time (usually 12-18 months).

Low swelling risk: The gel is fine and the probability of postoperative swelling and nodules is low.

Moderate support: Suitable for parts requiring moderate support (such as apple muscle).


Cross Linked Hyaluronic Acid Dermal Filler


Compared with American J brand related products, it can be found that there is equality in the important indicators below, but from the perspective of effect durability, our products can be maintained for a longer time.


                                 Gel Type
Index

Sub-skin

JXX


Deep

JXX


Derm

JXX


Fine

JXX

Elasticity Pa

550 -700

665

500 -650

398

250-400

214

150-200

156

Viscosity Pa

180 -280

49

150-250

41

40-100

74

20-40

68

HA
mg/mL

24

25

24

20

22

24

20

24

Maximum water absorption %

265

253

252

227

353

515

450

580

Effect maintenance time

24 month

18-24 month

24 month

24 month

18-24 month

>12 month

12 month

>9 month


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